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Avoiding the Immune Attack: Daniel Anderson, Ph.D. at TEDxDelMar

Our theme for TEDxDelMar 2011 was "A Search For A Cure". In this video, Dr. Anderson gives us his talk entitled "Avoiding the Immune Attack". Dr. Anderson's research is centered on developing new materials for medicine. One particularly important problem of interest to Dr. Anderson is the quest to develop nanoparticles that support the therapeutic delivery of drugs and macromolecules, inside of specific cell targets, in vivo. There are many macromolecular drugs, such as DNA, RNA and some proteins, with great therapeutic potential that will only function when inside of a cell. Furthermore, many drugs are non-functional or even toxic if they do not get delivered to the correct cell-types in the body. The rational design of nanoparticulate drug delivery systems is often challenging, particularly when the design criteria are difficult to define. To address this challenge, he has developed fully automated, combinatorial systems for the synthesis, purification, characterization, and formulation of new biomaterials and nanoformulations. Materials identified using these approaches have shown great utility both in vitro and in vivo, including in non-human primate studies. He continues to focus our efforts towards developing next generation nanotherapeutics for cancer and other diseases, and to develop an understanding of the structure/function relationships between nanoparticle structure and biological activity. In addition to nanotherapeutics, Dr. Anderson's group is interested in developing advanced biomaterials for a range of applications In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.
Length: 12:17


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