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Preventing and Treating Complications -- What's New? Nigel Calcutt, Ph.D. at TEDxDelMar

Our theme for TEDxDelMar 2011 was "A Search For A Cure". In this talk, Dr. Calcutt gives us his talk entitled "Preventing and Treating Complications -- What's New?" Dr. Nigel Calcutt received his Bachelor of Science degree in Zoology in 1985 and his Doctor of Philosophy degree in Physiology and Pharmacology in 1988, both from the University of Nottingham. He was then a Postdoc Fellow in Pharmacology at St. Bartholomews Hospital, University of London, UK. Dr. Calcutt was appointed in 1993 as Assistant Adjunct Professor of Pathology at UCSD. He was promoted to Professor in July 2005. Dr. Calcutt's research is focused on mechanisms of peripheral nerve disease and the identification of new therapeutic approaches to prevent onset of neuropathy or alleviate symptoms of an existing neuropathy such as sensory loss or pain. Most students and Fellows in his laboratory work on cellular and animal models of diabetic neuropathy although we also have projects looking at the toxic neuropathies that are side effects of certain cancer drugs and at models of HIV-associated peripheral neuropathy. He has adopted a multi-disciplinary approach to addressing the etiology of diabetic neuropathy and apply a diverse array of techniques that range from molecular and biochemical investigations of fundamental disease mechanisms to physiologic and behavioral assessments of nerve function and the efficacy of potential therapeutic strategies. He also collaborates with a number of biotechnology and pharmaceutical companies, so that the etiologic mechanisms that he proposes can be tested by rational drug design and in vivo pharmacology and ultimately by clinical trials. Students wishing to work in his laboratory must want to appreciate the full spectrum of a disease process and be flexible enough to answer research questions by application of a range of experimental techniques. In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.
Length: 18:52

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