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Triple Helix

Although the chemistry was wrong, Linus Pauling's triple-stranded DNA model was a catalyst for James Watson and Francis Crick to solve the structure of DNA. Originally created for DNA Interactive ( ) TRANSCRIPT: This is Linus Pauling's failed attempt to predict the structure of DNA. The problem with his triple helix model is that the phosphates form the helical core, with the bases pointing outwards. This would be impossible under normal cellular conditions. Each phosphate group is negatively charged, and so many negative charges forced together would repel each other, literally driving the structure apart.
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