Main Profile

At A Glance

Susan Lindquist Part 2: Protein Folding cont'd and Prions English Subtitle

http://www.ibioseminars.org/lectures/cell-bio-a-med/susan-lindquist/susan-lindquist-part-2.htmlIn the case of the yeast prion [PSI], the misfolding of the Sup35 protein results in a simple change in metabolism. When misfolded Sup35 is passed from mother cells to their daughters, this metabolic change is inherited. This unusual genetic mechanism changes the organism in a heritable way due to a self-perpetuating change in protein conformation with no change in its DNA. The mechanism of epigenetic inheritance we have delineated provides a one-step process for the acquisition of complex traits and affords a route to the genetic assimilation of unstable traits that are not yet encoded in the genome.
Length: 26:09

Contact

Questions about Susan Lindquist Part 2: Protein Folding cont'd and Prions English Subtitle

Want more info about Susan Lindquist Part 2: Protein Folding cont'd and Prions English Subtitle? Get free advice from education experts and Noodle community members.

  • Answer

Ask a New Question