http://www.ibioseminars.org/index.php?option=com_content&view=article&id=717&Itemid=710 In Part 2, Poo expands upon the "cells that fire together, wire together" idea. He describes experiments investigating the requirement of the timing of pre- and postsynaptic neuronal spiking in the modification of synaptic strength by correlated activities. He showed the importance of the order of spiking in the pre- and postsynaptic neurons, and implication of this "spike timing-dependent plasticity" (STDP) in learning and memory.
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