http://www.ibioseminars.org/index.php?option=com_content&view=article&id=712&Itemid=703 In Part 2, Lehmann focuses on the role of RNA regulation in germ cell development. A series of regulatory cascades allows the spatial and temporal regulation of maternal RNA translation that in turn regulates the specification of primordial germ cells, migration of these cells to the gonads, transcription in early germ line stem cells, and maintenance of germ line stem cells in the adult animal.
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