http://www.mindbites.com/lesson/1469 for full video. http://www.mindbites.com/series/367 for a bundle of videos on Events of DNA Replication. For an even broader bundle of videos that cover Molecular Genetics and the events of DNA Replication, check out http://www.mindbites.com/series/365 . To search for topic-specific help in our library of 400+ video products for Biology, please refer to our Biology category at: http://www.mindbites.com/category/22-biology . To check out our full Biology video course, with 390+ videos included, refer to: http://www.mindbites.com/series/441-biology . In this lesson, Professor Wolfe provides a complete overview of the replication of DNA, beginning with its structure. DNA has a double-helix structure of nucleotides, which made-up of a sugar, a phosphate, and a base. The strands are antiparallel, meaning they run in opposite directions, known as the 5' strand and the 3' strand. DNA replicates by the semi-conservative method of replication. Professor Wolfe explains how DNA polymerase only reads in one direction, from 3' to 5', and therefore creates ""replication bubbles"" in order to replicate the DNA twice as fast. This creates leading and lagging strands, which require RNA primer and Okazaki fragments added to the lagging strand in order for the process to work properly. At the end of the strands, which lack the free OH molecule needed to complete the process, telomeres are used to protect against a loss of information. This lesson is perfect for review for a CLEP test, mid-term, final, summer school, or personal growth! Taught by Professor George Wolfe, this lesson was selected from a broader, comprehensive course, Biology.
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