Frontiers of Biomedical Engineering (BENG 100) Professor Saltzman motivates the need for tissue engineering, and describes the basic elements of the tissue engineering approach. Professor Saltzman defines three different types of tissue transplants: autografts, allografts, and xenografts. An online resource for organ donors/recipients is presented, which stresses the great need for donors, and the important contribution of tissue engineering in producing/growing organs that can be used for this purpose. Next, Professor Saltzman compared drug and gene therapy, and discusses the use of stem cell in tissue engineering for wound healing. The need for compatible biomaterials to support growth and differentiation of stem cells into functional organ is also highlighted. 00:00 - Chapter 1. Introduction to Tissue Engineering 06:15 - Chapter 2. Challenges in Organ Transplantation 17:37 - Chapter 3. Cell Culturing in Tissue Engineering 32:34 - Chapter 4. Tissue Engineering in the Regulation of Healing Processes Complete course materials are available at the Open Yale Courses website: http://open.yale.edu/courses This course was recorded in Spring 2008.
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